I know from various sources that Sam is being held and watched over by Mudokons (slaves, presumely) and numerous Shrinks (heh) and she sits on a straw bed. She has the top of a Mudokon, but the abdomen is...a large blob, really. She was also designed with a nanny like face, so I'd expect her to have an old, kindly woman's voice.
The Glukkon queen has two designs. One is like a large worm with a huge head at the front, and calws down its length, while the other (final, I think) is the top of a Glukkon (arms, not as long as normal Gluks, vestigial legs etc.) and coming form her...well, a*s really is the main blob, not as large as Sam's but with numerous teats hanging off the sides. She is carried around by Kinto slaves.
I'd think she may be a boss, if not the only Glukkon queen in existance (I'd presume there's more than one over the whole world), and Sam would be resuced right near the end of the quintology, with a 'our future is secure' message, or rescued part way through and you continue to witness The Industrialists demise afterwards until they're pretty much eradicated or whatever.
I have no real comments on Skillya. Could appear any time.
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