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I guess the analogy for me would be saying that the Tour De France is less legitimate than the London Marathon, because competitors in the former use bicycles and can therefore move faster.
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And also because of the doping.
It might help to not view a TAS as a demonstration of skill*, but as means of entertainment. Some TAS's are very interesting: since reaction time isn't an issue, they can show off some crazy things that a human just couldn't do. However, O:AO and O:AE don't lend themselves to TASing in the same way, since they often look like regular speedruns, just without mistakes.
*Not that it's easy to make a good TAS. The idea is to aim for perfection, not a speedrun where you can redo your mistakes.