At the beginning of Munches Oddysee (the first movie, you can download it at gamespot, 45.5. megs!)...it shows the inside of Munches chest and stomach (under x-ray)..it has his heart beating and stuff. I would say they have pretty similar organs to Earth creatures.
Also, on Oddworld.com, you can look under Mudokon and Gabbit and you can see there skeleton, maybe organs.
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