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It has always struck me as weird that weed is illegal almost everywhere except for Holland and that everyone keeps believing it is so harmful, while the stuff has been legally for sale for as long as I can remember and I don't remember weed ever causing any sort of problem.
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Actually in case of abuse it causes severe mental disorders, such as schizophrenia and psychosis, especially in those users who are initially prone to such disorders (this kind of people don't even have to abuse it to aquire mental problems). Otherwise it's not harmful.
My opinion is that drugs should be used only as a form of medication. Though drug abuse problem can't be completely solved only through bans - it's more of a social and cultural problem. Persecution of heavy drug manufacturers and dealers is very important, however.