In the Swartzchild solution, which describes the spacetime outside of a sphere of matter and also a black hold in a matter-free universe, r is the distance from the center of the sphere/black hole.
ds2 = −(1 − 2M/r) dt2 + 1/(1 − 2M/r) dr2 + r2 dΩ2.
As r gets smaller the equation gets closer to infinity. At r=0 it reaches it. Or not, since it's usually considered to be undefined. But in a black hole, r=0 is the singularity. That is where the laws of physics as we understand them break down, because our only way of describing it returns as a divide by zero error.
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