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That's fair, but the point stands that if you value your own life less than non-existence, and your personal strife isn't particularly significant, then you're a bit of a shithead.
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They're not shitheads, they're sick. No one decides that nothings matters to them anymore, it's thrust upon them, sometimes as a result of events that make the reaction somewhat understandable, and sometimes for no discernible reason at all. When all the things (an there are many) that previously made your life worthwhile no longer have any effect on you, ipso-facto life loses its value.