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Are people with Downs Syndrome infertile by default or only in certain cases? And there are a lot more mental handicaps where becoming a parent probably isn't the wisest idea so the discussion remains ongoing.
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If Wikipedia is to be trusted, almost all males with Downs Syndrome are infertile (only three cases ever recorded of one becoming a father) and females have much lower fertility, as well as many problems related to childbirth.
So that partly knocks back my last post. Hmmm.