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There is no point denying that stuff like that can happen after a single use. But the chances of that aren't very high.
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Yes there is. I'm denying it right now. That person either had a chemical imbalance, or was dealing with some serious personal shit. Smoking pot is not going to do that to someone. It may do that to them for the duration of their high, but once that shit wears off, the symptoms are not going to persist.