I haven't yet. I may do this a lot this year in university mind you. I'll let you know how it goes..
I think my most played drunk game is Tekken 2 or Driv3r..
Tekken is generally trying to complete it whilst intoxicated.
Driv3r is.. well, a festivity of glitches and endless sniggering for hours.
Seriously, you haven't lived until you've drunkardly watched a sped-up replay on a driv3r Take A Ride whilst listening to this:
http://www.youtube.com/watch?v=iUuQEKjuo7c