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I think I'd make a miniature city. Then I could make little guys and street lamps to go with it. I'll never get this though, because I know I'll just screw it up and only use it so much.
And then since It's made out of the same plastic that Lego is built out of, I might make my own little bits and bobs for it. 
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I'd do this across my entire house/room. Build little pipes into the ridges along the walls, piece together a small inclinator for stairs, use a system of motors and tracks to create the illusion of people walking around, and see if adding a flammable liquid into the lego-plastic mix is possible.
After igniting a portion of the 'city' a jury-rigged fire-alarm system will speed up all of the motors and small poles will raise the small people's hands as they go by, making them appear to be panicking. The fire will be controlled, but 'guided' to the inclinator, where all of the people will have grouped to escape. The fire will burn through the inclinator's support wires and drive belt and it will crash, trapping all of the people inside and incinerating them.