I've done back-to-back runs, where I save them all first, and kill as many as possible next. Though there are instances where you can kill them creatively and hilariously, way too many Muds are nowhere near the convenient bone drill / pit / high explosive / shockwall, and as such are a hassle. Also, by simply killing some of them, you miss out on the puzzle involved had you saved them.
Now a combination of the two runs - THAT'S fun.
|