You can be a member of ALL guilds if you want, although some Dark Brotherhood missions conflict with certain factions (which is logical), especially the Mage's Guild, so you'll want to do that one first. Dark Brotherhood is the best anyway.
If you want to get kicked out of a Guild, just kill one of the members and pay your fine. You can't get kicked out of certain single-mission factions though... like Order of the White Stallion or Order of the Dragon. At least... I don't think you can.
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