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Nothing you just said is true. Chemical changes are extremely hard to reverse. Your entire body was created and functions on chemical change. It is biologically impossible, because DNA molecules are so insanely complex that changing one gene could affect the entire organism in ways that are unforeseen. You may think the idea sounds cool, but it's bullshit.
And metaphysics is not a science. Who you jivin' with that cosmik debris?
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I didn't call metaphysics science. It's name implies it ISN'T science anyway. It's "beyond physics".
Chemical changes can be very easy to reverse. Le Chartellie's principle gives several ways of altering the balance of an equation if you want it to go backwards. Most organic reactions are inefficient enough that they can be reversed.
DNA is unbelievable complex, but that doesn't mean it can't change or be changed. And as you said, you'd only have to change a little to get big results. To quote Keaalu/Teal: "I'm 50% banana {geneticaly}".
The only "trick" is to get a forced mutation of DNA specific to shifting... which sounds far too complex to be possible, which is where you need to bring in the Mind {which we don't fully understand, anyway} and things beyond the scope of science.
Just because science says "no" doesn't mean it's flat fact. Remember when physicists said "bees can't fly"?