I don't think they meant this happens after the quintology, just that its happened after MO and before ME (If and when ME comes into existance).
I don't think the structure of the super species needs to play a part in how far industrialists go. We don't know how long they glukkons have been in charge, and its reasonable to assume that there are places on the fringe of these industrialist centers that only partially benefit. The clakkerz and Wolvarks of OSW appear to be part of this trend. Western society has a habit of creating marginalized peoples and levels of connection. The area in the game is affected, but not overrun.
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