A medical problem, by definition, is an abnormal state of affairs within your biological system. Generally the effects of the abnormality are negative (hence the term problem) and so we assume that this will degrade performance. But it MUST be in the early stages for him to be doing what he's doing. If it was really bad off he'd have little buckets out asking for money. Oh, and just so we're all sure; Do we get the impression that Stranger is keeping this medical problem secret from the townsfolk? (not that running around shouting about your diseases is a good way to get work)
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