Where is the phrase "medical problem" coming from? I must have skipped it, somehow. I do recall that OI has said Stranger's weakness would be mental, not physical, so perhaps part of his problem is that he considers what might be a natural transformation as this "medical problem" that's been stated. You know, hunter becomes the hunted; "am I a man or a beast?" Stop this de-evolution; etcetera, etcetera. It could be Steef's are supposed to become the Centaur or minotaur type thing, and he thinks that the transformation would degrade him, or even just make him vulnerable.
I just realized (but this may have been covered before) that the images we've seen of the transformed Steefs are generally tranquil (exceting the roaring poster). Maybe the physical growth of the horns also represents a transfer of power from physical to spiritual. But who knows. I'm curious about what kind of hip and elbow joints would allow for the bi-pedal (walking) to quadrapedal (running) switch. He must have a kicking skeletal structure.
Oh, and I always assumed the transformation would happen once and remain the same for the rest of the game.
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