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Seeing as how it'll take place on an entirely different continent...
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Actually, Alf has pretty much said in Dear Alf that OW4 takes place in Mudos.
I'm not sure if Glukkons are going to turn up - I'm not sure Mudokons or Sligs will, since we've only seen early material from the production of the game, and all sorts could have changed since then. Same would go for Vykkers, except since we've seen one in an actual storyboard, I think it's more likely.